Granulomatosis With Polyangiitis (GPA Wegener's)

Best Granulomatosis with Polyangiitis (GPA) Doctor in Jaipur
What is Granulomatosis With Polyangiitis?

GPA is a multisystem autoimmune disease where the immune system mistakenly attacks the body’s own blood vessels, leading to inflammation and tissue damage. Over time, this can affect various organs:

  • Nose and sinuses: Persistent nasal blockage, crusting, or bleeding.

  • Lungs: Cough, breathlessness, and sometimes coughing up blood.

  • Kidneys: Blood or protein in urine, swelling in legs, and fatigue.

  • Joints and skin: Pain, rashes, and skin ulcers.

Because GPA symptoms resemble common infections, it often goes undiagnosed for months. Early recognition and treatment under a specialist like Dr. Aadhaar Dhooria are essential to prevent organ damage and improve outcomes.

Common Symptoms of GPA

The symptoms of Granulomatosis with Polyangiitis vary depending on the organs affected, but common signs include:

 

General Symptoms:-

 

  • Persistent fatigue and weakness

  • Fever, night sweats, or weight loss

  • Joint or muscle pain

Ear, Nose, and Throat (ENT) Symptoms:-

 

  • Recurrent sinus infections

  • Nasal crusting or nosebleeds

  • Ear infections, fluid buildup, or hearing loss

  • Sores inside the nose or mouth

Lung Symptoms:-

 

  • Chronic cough (sometimes with blood)

  • Shortness of breath

  • Chest pain or tightness

Kidney Symptoms:-

 

  • Blood in urine

  • Swelling in legs or ankles

  • High blood pressure

Other Symptoms:-

 

  • Eye redness, double vision, or vision loss

  • Numbness or weakness in limbs

  • Skin ulcers or rashes

If you notice a combination of these symptoms, especially those involving the sinuses, lungs, or kidneys, you should consult Dr. Aadhaar Dhooria, an experienced Granulomatosis with Polyangiitis specialist in Jaipur.

Causes and Risk Factors

The exact cause of GPA is not fully known, but it is believed to result from an abnormal immune system response. Factors that may contribute include:

 

  • Genetic predisposition

  • Certain infections

  • Environmental or chemical triggers

The condition is more common in adults aged 40–65 but can occur at any age.

Treatment for Granulomatosis with Polyangiitis (GPA)

Treatment for GPA focuses on controlling inflammation, preventing organ damage, and maintaining long-term remission. The treatment plan is tailored to each patient’s needs.

 

1. Induction Therapy (to control active disease):-

 

  • Corticosteroids to quickly reduce inflammation

  • Immunosuppressive drugs like cyclophosphamide or methotrexate

  • Biologic therapy (Rituximab) for severe or relapsing cases

2. Maintenance Therapy (to prevent relapse):-

 

  • Lower doses of immunosuppressive medications such as azathioprine or methotrexate

  • Regular monitoring of organ function and medication side effects

3. Supportive Care:-

 

  • Preventive measures against infections

  • Bone health management during steroid therapy

  • Periodic check-ups to monitor for disease recurrence

With appropriate treatment and follow-up under a specialist like Dr. Aadhaar Dhooria, many patients achieve long-term remission and lead healthy, active lives.

Why Choose Dr. Aadhaar Dhooria for GPA Treatment in Jaipur

  • Expertise in Autoimmune and Vasculitic Diseases: Dr. Dhooria specializes in managing complex autoimmune conditions like GPA, ensuring accurate diagnosis and targeted therapy.

  • Comprehensive and Multidisciplinary Care: Coordination between ENT, pulmonology, and nephrology for complete patient management.

  • Personalized Treatment Plans: Individualized therapy according to disease severity, organ involvement, and patient response.

  • Advanced Facilities: Access to modern diagnostic tools and evidence-based treatment approaches.

  • Long-Term Follow-Up: Continuous monitoring to detect relapses early and maintain remission.

When you choose Dr. Aadhaar Dhooria, you receive compassionate, patient-centered care and the latest treatment protocols for Granulomatosis with Polyangiitis in Jaipur.

When to Consult a Specialist

If you have ongoing sinus problems, unexplained cough, blood in urine, or persistent fatigue that does not respond to standard treatments, it’s time to seek expert advice.
Early evaluation by Dr. Aadhaar Dhooria, the best GPA doctor in Jaipur, can make a significant difference in controlling the disease and preventing complications.

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+91- 8955205541

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